The Formidable Fifteen: Diving into the Risk Factors for Dementia

14. Diabetes – The Hidden Catalyst

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Diabetes - The Hidden Catalyst
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Diabetes, characterized by elevated blood sugar levels, is another health condition that carries wide-ranging implications. Its influence extends to various aspects of health, from heart to kidney health, and significantly, to brain health. Both type 1 and type 2 diabetes have been identified as potential risk factors for dementia, including Alzheimer’s disease and vascular dementia.

The link between diabetes and dementia lies in the havoc high blood sugar levels can wreak on our body. These high sugar levels can, over time, damage both large and small blood vessels throughout the body.

When these vessels supply the brain, this damage can lead to cognitive decline. Additionally, diabetes can also lead to other health problems like heart disease and stroke, which, as we have learned, are risk factors for dementia themselves.

But why does this happen? High blood sugar levels can lead to the formation of harmful substances known as advanced glycation end products (AGEs).

These substances can cause inflammation and oxidative stress, harming brain cells and leading to cognitive decline. Diabetes can also damage blood vessels, impairing blood flow to the brain and potentially leading to vascular dementia.

To lower the risk of dementia linked to diabetes, managing blood sugar levels becomes a top priority. Regular monitoring, taking prescribed medication consistently, adhering to a balanced diet low in refined sugars, engaging in regular physical activity, and maintaining a healthy weight are all crucial steps. With proper management, diabetes can be controlled, and the associated dementia risk reduced. (14)

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