Cause 9: Asthma and EoE Connection
At first glance, asthma, a respiratory condition, and EoE, an esophageal disorder, might seem worlds apart. But dig a little deeper, and you’ll find that the two might be more interconnected than one might presume. Both conditions share a common foundation: an overactive immune response to perceived threats, leading to inflammation.
Asthma triggers an immune-mediated response in the lungs, leading to inflammation of the airways. Similarly, in EoE, the immune system, particularly eosinophils, attacks the esophagus. The common denominator here is the body’s inflammatory response. The presence of one inflammatory condition can sometimes predispose an individual to another, hence the observed link between asthma and EoE.
Individuals with asthma have an inherently heightened immune response. Their body is always on high alert, ready to tackle asthma triggers like pollen or dust. This heightened state can sometimes spill over to other parts of the body, including the esophagus. Thus, when exposed to potential EoE triggers, asthmatics might have a predisposed esophagus, more vulnerable to an eosinophilic attack.
For asthmatics, it’s crucial to recognize the potential risk of developing EoE. Regular screenings, understanding the symptoms of EoE, and prompt medical interventions can help manage this dual threat. On the flip side, individuals diagnosed with EoE should also be evaluated for asthma, given their intertwined nature. (9)
