Cause 4. Autoimmune Disorders: When the Body Attacks Itself
Autoimmune disorders are conditions in which the immune system mistakenly attacks healthy cells in the body. In some cases, these disorders can lead to aplastic anemia. The immune system may target bone marrow cells, resulting in a reduced production of blood cells.
Lupus, also known as systemic lupus erythematosus (SLE), is an autoimmune disease that can cause aplastic anemia. In patients with lupus, the immune system mistakenly attacks various tissues and organs, including the bone marrow. This can lead to bone marrow suppression and the development of aplastic anemia.
Rheumatoid arthritis (RA) is another autoimmune disorder that can cause aplastic anemia. RA primarily affects the joints, causing pain, swelling, and stiffness. However, in some cases, the immune system may also attack the bone marrow, leading to the reduced production of blood cells and the development of aplastic anemia.
Treatment for aplastic anemia caused by autoimmune disorders often focuses on suppressing the immune system to halt the attack on bone marrow cells. Immunosuppressive medications, such as corticosteroids and cyclosporine, are commonly used for this purpose. In some cases, a bone marrow transplant may be recommended for patients with severe aplastic anemia caused by autoimmune disorders. (4)
