Cause 7. Pregnancy: A Complex Relationship
Aplastic anemia during pregnancy is a rare but serious complication that can pose significant risks to both the mother and the developing fetus. The exact cause of aplastic anemia during pregnancy is not well understood, but it is believed to involve a complex interplay of hormonal, immunological, and genetic factors.
Pregnancy-related changes in hormone levels, such as increased estrogen and progesterone, may affect bone marrow function and lead to the development of aplastic anemia. Additionally, the immune system undergoes significant changes during pregnancy to prevent the rejection of the fetus. These changes may contribute to the development of aplastic anemia in some cases.
Treatment for aplastic anemia during pregnancy can be challenging, as many medications used to treat the condition may pose risks to the developing fetus. Supportive care measures, such as blood transfusions and the use of certain growth factors, can help manage symptoms and improve maternal and fetal outcomes. In some cases, immunosuppressive therapy may be considered, but the potential risks and benefits must be carefully weighed.
Postpartum, some women may experience spontaneous recovery from aplastic anemia as their hormone levels and immune system return to normal. However, ongoing monitoring and follow-up care are essential to ensure the mother’s long-term health and well-being. (7)
