8. Vitamin E Deficiency: When Nutrition Takes Center Stage
Nearing the end of our list, we encounter a cause that might surprise some—Vitamin E deficiency. Though relatively rare, a severe lack of this nutrient can lead to ataxia—specifically, a condition known as ataxia with vitamin E deficiency (AVED).
Vitamin E is a powerful antioxidant that protects our cells from damage. It is particularly important for nerve health.
In AVED, the body is unable to absorb or, in some cases, transport vitamin E effectively, leading to progressive nerve damage. This damage predominantly affects the sensory neurons and the cerebellum, leading to coordination and balance issues characteristic of ataxia.
The connection between vitamin E and ataxia underscores the vital role nutrition plays in our health. It highlights the importance of a balanced diet, rich in a variety of nutrients. However, it’s crucial to note that AVED is often due to genetic mutations affecting the body’s ability to absorb or transport vitamin E, rather than a lack of dietary intake.
Nonetheless, once diagnosed, AVED can often be managed effectively with high-dose vitamin E supplements. Regular follow-up and monitoring are crucial, as early and continuous vitamin E supplementation can prevent symptom progression and sometimes even reverse some symptoms. (8)
