5. Infections: External Invaders and Internal Turmoil
Infections, especially those targeting the digestive system, might have a say in the Crohn’s narrative.
Pathogens like Salmonella or E. coli, which cause gastrointestinal infections, can lead to short-term inflammation. For some individuals, this acute phase might transition into chronic inflammation, characteristic of Crohn’s.
Even after the infectious agent is dealt with, its legacy might linger. It can lead to alterations in gut microbiome or stimulate a sustained immune response, both potential contributors to Crohn’s.
Beyond bacteria, certain viruses have been implicated. For instance, the Epstein-Barr virus, best known for causing mononucleosis, has been linked to an increased risk of Crohn’s in some studies.
If certain infections do heighten the risk of Crohn’s, then targeted vaccinations might offer a preventive strategy. This angle, still in its infancy, offers hope for the future. (5)
