9. Hormonal Shifts: The Tides Within
The body’s internal chemical messengers, hormones, may also play a part in Crohn’s disease.
The onset of Crohn’s often coincides with puberty in many patients. The hormonal upheavals during this phase might act as a trigger, especially in genetically predisposed individuals.
Women appear to have a slightly higher risk of developing Crohn’s. Fluctuating estrogen levels, especially during menstruation, pregnancy, and menopause, might influence disease activity.
Chronic stress leads to elevated cortisol levels. This stress hormone can impact gut permeability and function, potentially playing a role in Crohn’s development or exacerbation.
If hormonal imbalances are proven to be significant contributors, endocrine therapies might be explored as potential treatments or management strategies. (9)
