Cause 8: Drug-induced Hemolytic Anemia
The Unintended Consequences of Medications
Drug-induced hemolytic anemia occurs when certain medications trigger the immune system to attack and destroy red blood cells. Examples of drugs that can cause hemolytic anemia include penicillin, cephalosporins, quinidine, and levodopa.
The mechanism by which these medications cause hemolytic anemia may involve the drug or its metabolites binding to red blood cells, leading the immune system to identify these cells as foreign and target them for destruction.
Treatment for drug-induced hemolytic anemia involves discontinuing the offending medication and providing supportive care, such as blood transfusions if necessary. In some cases, corticosteroids or intravenous immunoglobulin (IVIG) may be used to suppress the immune response and reduce the severity of the anemia.
Awareness of the potential for certain medications to cause hemolytic anemia and close monitoring of patients on these drugs can help prevent severe complications and ensure appropriate management of the condition. (7)
