Medication 6: Anticholinergics: Addressing Tremors
Anticholinergic medications have been used to treat Parkinson’s disease for many years, although their use has declined with the development of newer, more targeted therapies. These drugs work by blocking the action of acetylcholine, a neurotransmitter that can contribute to tremors in Parkinson’s patients. Examples of anticholinergic medications include benztropine (Cogentin) and trihexyphenidyl (Artane).
While anticholinergics can be effective in reducing tremors, they are generally less effective in managing other Parkinson’s symptoms, such as rigidity or bradykinesia.
Due to their limited effectiveness in addressing the full range of Parkinson’s symptoms, anticholinergics are typically reserved for patients who primarily experience tremors or for whom other medications are not suitable.
Anticholinergic medications can cause a range of side effects, including dry mouth, blurred vision, constipation, and urinary retention. They may also contribute to cognitive issues, particularly in older patients. As with all Parkinson’s medications, healthcare providers will closely monitor patients taking anticholinergics and adjust treatment plans as needed to balance symptom relief with potential side effects. (6)
