2. Progressive Memory Loss: A Hidden Indicator of CAA
The second significant symptom of CAA is progressive memory loss. It’s essential to recognize that this is not the typical forgetfulness that accompanies aging. CAA-related memory loss is more pronounced, affecting daily activities and routines, and tends to worsen over time.
The cognitive decline associated with CAA often starts subtly. An individual might start forgetting familiar names or misplacing items more frequently.
They may also experience difficulty remembering recent events or conversations. Over time, this can progress to more severe memory loss, including forgetting significant life events or personal details.
The mechanism behind memory loss in CAA is tied to the brain areas most affected by the protein build-up. The amyloid-beta proteins often accumulate in the blood vessels supplying the brain’s memory and cognition centers. As these vessels become compromised, the brain regions they serve can suffer from reduced blood flow, leading to the observed memory loss and cognitive decline.
However, memory loss is not exclusive to CAA. It’s a symptom seen in many neurological disorders, including Alzheimer’s disease and other types of dementia. (2)
