9. Mood and Personality Changes: The Emotional Toll of CAA
Changes in mood and personality can also be a part of the CAA picture. Individuals with CAA might display symptoms of depression, anxiety, irritability, or apathy. They may become socially withdrawn or display changes in their behavior or personality that are out of character.
These changes can occur due to the impact of amyloid-beta proteins on the brain areas responsible for regulating mood and behavior. In addition, dealing with other symptoms of CAA, like memory loss and physical impairments, can also lead to frustration, anxiety, and depression.
A once outgoing and social individual might become more introverted and less interested in social activities. Or someone who was typically calm and patient might become more irritable or prone to mood swings. These changes can be distressing for both the individual and their loved ones, adding an additional layer of complexity to the management of CAA. (9)
