Cause 2: The Gender Factor – Why Women are More Affected
Gender disparity in Graves’ disease is another intriguing aspect. The condition disproportionately affects women, who are approximately seven to eight times more likely to develop it than men. This finding has led to questions about the role of sex hormones, such as estrogen and progesterone, in the development of Graves’ disease.
Numerous studies have focused on understanding why women bear the brunt of this disease. Some theories suggest that the female sex hormones may somehow interact with the immune system, making women more susceptible to autoimmune disorders. However, it’s important to note that these theories are still under investigation, and the exact mechanisms remain elusive.
Interestingly, Graves’ disease often first appears or worsens during times of hormonal change for women, such as pregnancy or menopause. This further supports the hypothesis that hormones might be a contributing factor.
However, despite being less affected, men are not entirely immune to Graves’ disease. Their risk might be lower, but they should still be aware of the potential symptoms and seek medical help if needed.
Ultimately, while gender is undoubtedly a significant factor, it is just one of many contributing to the complex tapestry of causes underlying Graves’ disease. (2)
