10. Darkened Skin Areas: A Visible Change
The last symptom on our list is the development of darkened skin areas, medically known as acanthosis nigricans. These patches can appear on the neck, armpits, and other folds of the skin, serving as a visible change and potential cause for concern.
This skin condition is linked to insulin resistance, a common issue in MODY. When the body becomes resistant to insulin, it results in elevated insulin levels in the bloodstream, which can, in turn, lead to the growth of skin cells and melanin, causing darkened areas.
Managing this symptom involves improving insulin sensitivity through lifestyle changes and medication. Adopting a balanced diet, regular exercise, and maintaining a healthy weight can all contribute to better insulin utilization.
Consulting a dermatologist can also provide additional treatment options, such as topical creams or laser therapy. It’s essential not to ignore this visible symptom, as it can be an indicator of underlying insulin resistance and requires medical attention. (10)
