Symptom 6. Numbness and Tingling Sensations: The Nervous System’s Response to Megaloblastic Anemia
Numbness and tingling sensations, often in the hands and feet, are another common symptom of megaloblastic anemia. These symptoms, also known as paresthesia, are due to nerve damage caused by a vitamin B12 deficiency, a common underlying cause of this type of anemia. This nerve damage can lead to peripheral neuropathy, a condition characterized by these uncomfortable sensations.
The sensation is often described as “pins and needles” or a “prickling” feeling. It may also include feelings of cold, burning, or even extreme sensitivity to touch. The severity and duration of these sensations can vary from person to person, and they may become more pronounced over time if left untreated.
Along with the physical discomfort, these sensations can also cause psychological distress. The constant discomfort can be a source of anxiety and may disrupt sleep. Over time, this can lead to exhaustion and further contribute to feelings of anxiety and depression.(6)