Fact 5. Onset and Progression: The MSA Timeline
Let’s look at the typical onset and progression of MSA. This disorder is generally classified as a late-onset disease, which means symptoms usually begin to appear when individuals are in their 50s or 60s. This isn’t a hard and fast rule, though, as MSA can occur earlier or later in life, though these instances are less common.
The progression of MSA varies between individuals but generally follows a gradual yet relentless course. Early symptoms may include fainting spells and problems with heart rate and blood pressure. As the disease progresses, symptoms typically worsen, and more signs may become apparent, such as difficulties with movement and coordination.
It’s important to note that the disease progression in MSA is typically faster than in other neurodegenerative disorders like Parkinson’s disease. While the rate of progression can differ from person to person, it’s common for individuals to become significantly disabled within a few years of onset.
One of the factors making MSA a particularly challenging condition is its unpredictability. The rate at which symptoms worsen and the types of symptoms that develop can vary widely among individuals. Some people might experience rapid deterioration over a few years, while others might have a slower progression of the disease. (5)
