Symptom 10: Thickening of the Skin
A less common, yet noteworthy symptom of Paget’s disease of the breast is a thickening of the skin. Just as the skin may become itchy, scaly, or reddened, it can also grow denser in certain areas. This symptom generally presents alongside other changes, such as nipple abnormalities or skin redness, and can be easily mistaken for an inconsequential skin condition, but should not be dismissed lightly.
Skin thickening in Paget’s disease differs from typical skin thickening seen in conditions like dermatitis or eczema. Instead of a widespread pattern, this thickening typically remains localized, often confined to the nipple or areola. The texture of the thickened skin can range from a leathery toughness to a more subtle rigidity that subtly distorts the skin’s usual suppleness.
The significance of skin thickening lies in the underlying mechanism causing it. This alteration is an external manifestation of the disturbance caused by cancer cells infiltrating the epithelial tissue of the breast. It’s the body’s response to the abnormal cell growth, leading to a change in the skin’s integrity and elasticity.
Upon noticing skin thickening, it’s crucial to consult a healthcare provider promptly. A thorough examination will be conducted to understand the extent and nature of the thickening. Additional tests, including imaging studies and potentially a biopsy, may be recommended to confirm the cause of the skin thickening.(10)
