10. Bleeding and Bruising: The Delicate Balance of Blood Clotting in Polycythemia Vera
Bleeding and bruising are symptoms experienced by some individuals with PV. These symptoms can manifest as frequent nosebleeds, bleeding gums, easy bruising, or prolonged bleeding from minor cuts and injuries.
The primary cause of bleeding and bruising in PV patients is an imbalance in blood clotting factors due to the excessive production of blood cells. This imbalance can cause the blood to become both more prone to clotting and less able to form stable clots, leading to an increased risk of bleeding and bruising.
In some cases, bleeding and bruising may also be linked to other underlying health conditions or the side effects of medications used to treat PV. It is essential to discuss this symptom with a healthcare professional to identify the cause and develop an appropriate treatment plan.
Managing bleeding and bruising in PV patients may involve medications to address the underlying cause of PV or modify the clotting factors in the blood. Patients may also benefit from lifestyle modifications, such as avoiding high-impact activities that can lead to injury, using a soft toothbrush to prevent gum bleeding, and being mindful of potential sources of bruising. Regular consultation with a healthcare professional is vital for monitoring and adjusting treatment plans to manage these symptoms effectively. (10)