4. Itching and Skin Redness: The Uncomfortable Side of Polycythemia Vera
Itching (pruritus) and skin redness (erythema) are common symptoms experienced by individuals with PV. These skin manifestations can be bothersome and may cause significant discomfort, affecting daily life and well-being.
Itching in PV is primarily attributed to the increased blood flow and the release of histamine, a substance involved in the body’s inflammatory response. The excessive histamine release can cause itching, particularly after exposure to warm water, such as during a bath or shower.
Skin redness in PV patients is often a result of the elevated number of red blood cells, leading to increased blood flow to the skin’s surface. This increased blood flow can cause the skin to appear flushed or reddish, particularly on the face, hands, and feet.
Managing itching and skin redness in PV may involve over-the-counter antihistamines or prescription medications to control the release of histamine. Patients may also benefit from using gentle skincare products, avoiding hot baths or showers, and wearing loose-fitting clothing made of natural fibers. Regular consultation with a healthcare professional is vital for monitoring and adjusting treatment plans to manage these symptoms effectively. (4)