Symptom 2. Enlarged Spleen (Splenomegaly): A Result of Overworking
The spleen is an organ that plays a crucial role in filtering and recycling old red blood cells. In individuals with thalassemia, the spleen may become enlarged, a condition known as splenomegaly, due to the increased workload placed upon it. This enlargement can cause various issues and complications for those affected.
One of the primary concerns with an enlarged spleen is the potential for it to become overworked and less efficient at its job. As the spleen struggles to keep up with the increased demand, it may become less effective at filtering and recycling red blood cells, leading to a worsening of anemia symptoms.
Additionally, an enlarged spleen can cause abdominal discomfort or pain, particularly in the upper left area of the abdomen. This discomfort can range from mild to severe and may be exacerbated by eating large meals, as the spleen can press against the stomach.
In some cases, splenomegaly may also increase the risk of infection, as the spleen plays a role in the immune system’s function. A compromised spleen may struggle to filter out bacteria, viruses, and other harmful substances, leading to a higher susceptibility to illness.
Lastly, an enlarged spleen can increase the risk of rupture, which is a potentially life-threatening emergency. In the event of a rupture, the individual may experience sudden, severe abdominal pain and require immediate medical attention. (2)
