Symptom 8. Iron Overload: A Dangerous Complication of Thalassemia Treatment
Iron overload is a common and potentially dangerous complication that can occur in individuals with thalassemia, particularly those who undergo regular blood transfusions as part of their treatment. Blood transfusions can introduce excess iron into the body, which can accumulate over time and cause damage to various organs, including the liver, heart, and endocrine glands.
One of the primary concerns with iron overload is the risk of liver damage. Excess iron can cause the liver to become inflamed, a condition known as hepatic iron overload, which can lead to fibrosis and eventually cirrhosis if left untreated. Additionally, iron overload can cause damage to the heart, resulting in conditions such as cardiomyopathy and congestive heart failure.
To manage iron overload in individuals with thalassemia, healthcare providers may recommend iron chelation therapy. This treatment involves the use of medications that bind to excess iron and help remove it from the body. By regularly monitoring iron levels and undergoing appropriate chelation therapy, individuals with thalassemia can minimize the risk of complications associated with iron overload. (8)
