Understanding the Causes of Sjögren Syndrome (Sjögren’s Syndrome, SjS, SS)

Cause 2: Hormonal Imbalance

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Hormonal Imbalance
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One might wonder, what connects hormonal fluctuations with an autoimmune condition like Sjögren Syndrome? Hormones, often underestimated, are the body’s silent regulators, ensuring that every physiological process occurs seamlessly. When they falter or fluctuate, the repercussions can manifest in myriad ways, including increasing susceptibility to conditions like Sjögren Syndrome.

Of the myriad hormones coursing through our veins, estrogen stands out in the context of Sjögren Syndrome. Beyond its crucial role in reproduction, estrogen has a lesser-known but profound impact on the immune system. Imbalances, especially a decline in estrogen levels, can make the immune system hyper-reactive, leading it astray and causing it to attack the body’s own tissues.

What leads to these hormonal imbalances? The reasons vary. Natural life stages like menopause, medical conditions such as polycystic ovary syndrome (PCOS), or even medical interventions like hysterectomies can cause shifts in hormone levels. And while these changes are natural or necessary, in some individuals, they can pave the way for autoimmune reactions, with Sjögren Syndrome being a potential outcome.

Awareness of the hormonal link to Sjögren Syndrome brings forth new therapeutic possibilities. Could hormone replacement therapy be an answer for some? Could adjustments in existing treatments reduce the risk? As researchers explore these questions, the hope is to find strategies that address the root cause, offering relief to those affected.

In the vast landscape of factors contributing to Sjögren Syndrome, hormonal imbalances carve a distinct niche. Recognizing this connection underscores the intricate web of interactions within our body, emphasizing the need for holistic treatments that address both the symptoms and their underlying causes. (2)

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