Cause 8. The Microbiome Imbalance: How Tiny Organisms Influence Atopic Dermatitis
Our skin is home to a diverse community of microorganisms, collectively known as the skin microbiome. In healthy skin, this microbiome maintains a delicate balance, protecting the skin from harmful pathogens and contributing to immune regulation. In atopic dermatitis, however, this balance is disrupted, leading to an overgrowth of certain microbes that can exacerbate the condition.
A key player in this microbiome imbalance is a bacterium called Staphylococcus aureus. This bacterium is found on the skin of many individuals with atopic dermatitis, and its overgrowth can lead to skin inflammation and worsening of symptoms.
Interestingly, this microbiome imbalance often occurs alongside a compromised skin barrier and an overactive immune response. The disrupted skin barrier allows for the overgrowth of S. aureus, while the immune system’s inability to control this overgrowth results in further inflammation and damage to the skin barrier. (8)