Fact 4: Rapid Progression of HSE
HSE is characterized by a rapid onset and progression of symptoms. It starts subtly, with the aforementioned flu-like symptoms slowly creeping in. At this point, the patient, and even healthcare providers, might not suspect anything more serious than a common viral infection. However, the deceptive calm of the early phase belies the storm that’s about to hit.
Once the virus has established itself in the brain, things start to escalate rapidly. Severe headaches become a persistent issue, an unrelenting pressure that seems to squeeze the skull from all sides. The pain can be debilitating, often not responding to regular pain relief methods.
It’s not just the physical discomfort that escalates. The neurological symptoms start to make their appearance during this stage. There can be sudden changes in personality and behavior, with patients displaying uncharacteristic aggression, apathy, or mood swings. Loved ones may notice these alterations, marking a significant shift from the patient’s normal demeanor.
One of the most alarming developments in this phase is the onset of seizures. These can range from minor focal seizures, which affect just one part of the brain, to major generalized seizures that involve the entire brain. They represent a serious escalation of the disease and require immediate medical attention.(4)