2. Cutaneous Lupus Erythematosus (CLE)
Cutaneous Lupus Erythematosus (CLE) is a variant of lupus that predominantly affects the skin. The term ‘cutaneous’ refers to the skin, and true to its name, the symptoms of CLE are primarily dermatological. While CLE primarily affects the skin, around 5-10% of individuals with CLE eventually develop SLE.
One of the most common types of CLE is Acute Cutaneous Lupus Erythematosus (ACLE), characterized by a distinctive rash often in a butterfly shape, much like in SLE. This rash typically affects the face, especially the cheeks and the bridge of the nose, but it can also extend to other areas of the body exposed to the sun. The rash can be a source of significant discomfort and may also cause emotional distress due to its visible nature.
Another subtype of CLE is Subacute Cutaneous Lupus Erythematosus (SCLE). Patients with SCLE develop non-scarring skin lesions that appear as red, scaly patches, often in sun-exposed areas. These skin manifestations can be triggered or worsened by exposure to sunlight, which is a common theme in lupus.
Chronic Cutaneous Lupus Erythematosus (CCLE), often known as Discoid Lupus Erythematosus (DLE), is the third subtype of CLE. It presents as disk-shaped, red, scaly, and thickened lesions that can cause scarring. Discoid lesions commonly occur on the scalp and face and can lead to permanent hair loss if they affect the scalp. (2)
