Cause 10. High Homocysteine Levels – An Overlooked Factor in Vascular Dementia
Homocysteine, an amino acid produced by the body, usually doesn’t make headlines in discussions about dementia. However, high levels of homocysteine have been implicated as a risk factor for vascular dementia. Excess homocysteine can damage the lining of the arteries, promoting the formation of blood clots and increasing the risk of stroke.
Additionally, high homocysteine levels can lead to atherosclerosis, where plaque buildup narrows the arteries, further compromising blood flow to the brain and setting the stage for vascular dementia. Indeed, several studies have found a correlation between high homocysteine levels and both cognitive impairment and vascular dementia, indicating a direct role of this amino acid in brain health.
Nutritional factors play a pivotal role in controlling homocysteine levels. Vitamins B6, B9 (folic acid), and B12 help break down homocysteine in the body. (10)
