Fact 2: The Triad of Burkitt Lymphoma
Burkitt Lymphoma doesn’t follow a one-size-fits-all pattern. Instead, it manifests in three distinct types, each with its own unique characteristics and factors. These include Endemic, Sporadic, and Immunodeficiency-related Burkitt Lymphoma.
Endemic Burkitt Lymphoma, also known as African Burkitt Lymphoma, primarily affects children in malaria-endemic regions of Africa. Interestingly, a significant percentage of these cases have been associated with the Epstein-Barr Virus (EBV).
Sporadic Burkitt Lymphoma, also known as non-African Burkitt Lymphoma, is the type most commonly found in the United States and Western Europe. Unlike the endemic form, sporadic Burkitt Lymphoma is not linked to a specific geographical area and affects a broader age group, including adults.
Immunodeficiency-related Burkitt Lymphoma, as the name suggests, predominantly affects individuals with compromised immune systems. This could include people living with HIV/AIDS or those who have undergone organ transplantation and are on immunosuppressive drugs.
These variations underline the complexity of Burkitt Lymphoma and the need for tailored treatment approaches. Understanding the differences between the three types of Burkitt Lymphoma can assist healthcare professionals in devising the most effective treatment plan. (2)
