Cause 3. Medications: Unintended Consequences
Certain medications can also cause vasculitis as a side effect, although this is a relatively rare occurrence. Medications that have been implicated in vasculitis include some antibiotics, antihypertensive drugs, and anti-inflammatory medications.
When a medication is responsible for vasculitis, the inflammatory process typically results from an abnormal immune response. The body may recognize the medication as a foreign substance, leading to the production of antibodies and activation of immune cells that mistakenly target blood vessels. This immune response can lead to blood vessel inflammation and damage.
It is important for both patients and healthcare providers to be aware of the potential risks associated with certain medications. When vasculitis is suspected to be caused by a medication, the first step in treatment is typically to discontinue the drug in question. In most cases, stopping the medication can lead to the resolution of the vasculitis symptoms. However, additional therapies may be required to manage any residual inflammation or damage to blood vessels.
In some cases, alternative medications may need to be considered to avoid the risk of vasculitis. This may involve switching to a different class of drugs or opting for a different treatment approach altogether. Close collaboration between patients and their healthcare providers is essential in determining the best course of action. (3)