Cause 7. Connective Tissue Disorders: A Related Health Issue
Connective tissue disorders, such as systemic lupus erythematosus (SLE) and scleroderma, are conditions characterized by inflammation and damage to various connective tissues in the body, including blood vessels. Similar to autoimmune disorders, connective tissue disorders result from a combination of genetic and environmental factors that trigger an abnormal immune response.
The relationship between connective tissue disorders and vasculitis is quite complex. Researchers believe that the underlying immune system dysfunction in these conditions may lead to the production of antibodies that attack blood vessels. This can cause inflammation and damage, resulting in vasculitis. In some cases, the vasculitis may be the initial symptom of an undiagnosed connective tissue disorder, making it essential for healthcare providers to consider this possibility when evaluating patients with vasculitis.
In cases of vasculitis caused by connective tissue disorders, treatment typically involves managing the underlying condition. This may include the use of immunosuppressive medications, such as corticosteroids, to reduce inflammation and prevent further damage to blood vessels. In more severe cases, additional therapies, such as immunoglobulins or biologic agents, may be required. (7)
