Cause 10. Body Mass Index and Obesity: The Heavy Burden of Excess Weight
In today’s world, rising obesity rates have become a global health concern, linked to a range of chronic diseases. However, few realize that the consequences of excess weight go beyond the commonly discussed conditions, extending to cancers like NHL.
A higher Body Mass Index (BMI), indicative of overweight or obesity, is not just about extra pounds. It reflects an altered metabolic state. Obesity triggers a cascade of internal changes, from hormonal shifts to chronic inflammation, both of which can set the stage for NHL.
Take, for instance, the hormone insulin. Elevated levels, often seen in obesity, can spur cell growth. While this might sound benign, unchecked cell proliferation is a hallmark of cancer. It creates an environment conducive to mutations and anomalous growth patterns.
Additionally, fat cells, especially those around the abdomen, are not inert. They actively secrete a range of substances, some of which can be pro-inflammatory. As discussed earlier, chronic inflammation is a potential risk factor for NHL.
The intertwined relationship between obesity, metabolic alterations, and NHL is a testament to the intricate nature of human health. It’s a vivid reminder that the choices we make, from what we eat to how active we are, have far-reaching implications, shaping not just our physique but our overall health trajectory. (10)