Symptom 2. Unseen Battles: The Fever’s Tale
Intermittent fevers are a classic hallmark of many infectious diseases, and African Trypanosomiasis is no exception. This common symptom is, in reality, an outward expression of the unseen battle between the invading Trypanosoma brucei parasite and the host’s immune system.
When the parasite first enters the bloodstream, it causes little disturbance. However, as it multiplies and spreads, the host’s immune system recognizes the threat and initiates a counterattack. The result? A fever. But this isn’t just any fever. It’s irregular, recurrent, and almost rhythmic in nature, reminiscent of the fevers seen in malaria.
The fever is often accompanied by chills, making for an uncomfortable duo. This dual manifestation of fever and chills tends to last for a few days before spontaneously resolving. However, just when the patient starts to feel better, the fever rears its ugly head again. This on-and-off pattern continues as the immune system battles the invading parasite, marking the hemolymphatic stage of African Trypanosomiasis.
Besides the discomfort, the fever plays an essential role in the body’s defense mechanism. It’s the body’s way of creating an inhospitable environment for the parasites, attempting to curb their replication and spread. It’s a fascinating demonstration of the body’s resilience and its ceaseless efforts to maintain homeostasis, even in the face of a stealthy adversary. (2)
