2: Environmental Factors – The Invisible Triggers of RA
Environmental factors can also play a crucial role in the development of rheumatoid arthritis. Researchers have discovered that certain substances, such as cigarette smoke and air pollution, can increase the risk of RA in genetically predisposed individuals.
Cigarette smoking, in particular, has been identified as a significant risk factor for RA. Smoking has been shown to induce inflammation in the body, leading to increased production of proteins that can trigger the autoimmune response associated with RA. Additionally, smoking can weaken the immune system, making it more difficult for the body to fight off infections and other potential RA triggers.
Exposure to air pollution, specifically fine particulate matter (PM2.5), has also been linked to an increased risk of developing RA. This type of pollution can cause inflammation in the body, similar to smoking, and may exacerbate the autoimmune response in susceptible individuals. (2)
