Top 10 Causes of Iron Deficiency: Uncovering What Leads to Iron Depletion

Cause 5: Poor Iron Storage

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Poor Iron Storage
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The body stores iron in a protein called ferritin, primarily found in the liver, bone marrow, and spleen. Some individuals may have low iron storage due to genetic factors, leading to an increased risk of iron deficiency.

Hereditary hemochromatosis is a genetic condition that impairs the body’s ability to regulate iron absorption, leading to the accumulation of excess iron in tissues and organs. While this condition primarily results in iron overload, treatment often involves bloodletting to reduce iron levels, which can lead to iron deficiency if not appropriately managed.

Low iron storage can also occur due to chronic diseases, such as chronic kidney disease, liver disease, or cancer. These conditions can interfere with the body’s ability to store and utilize iron, resulting in deficiency. Proper management of these chronic conditions is essential to prevent complications, including iron deficiency. (5)

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