Fact 2: Cirrhosis – More Than Just Scars
Cirrhosis, often perceived as just the aftermath of prolonged liver damage, plays a pivotal role in the prognosis of HCC. This condition, characterized by scar tissue replacing healthy liver tissue, impacts liver function on multiple levels. While cirrhosis is a result of various factors, including alcohol abuse, fatty liver, and viral hepatitis, its association with HCC is particularly significant.
Patients with cirrhosis have a weakened liver. This compromised state makes them more susceptible to developing HCC. Moreover, a liver affected by cirrhosis may not respond to treatments as effectively as a healthy one would. The already diminished liver function can further deteriorate when challenged by an aggressive cancer like HCC.
Furthermore, the presence of cirrhosis often limits the treatment options available. For instance, surgical interventions, which might be considered for patients without cirrhosis, can pose greater risks for those with this condition. The liver’s reduced capacity to heal and regenerate makes post-operative recovery challenging. (2)
